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Japanese Mushroom Complex · 30-day daily system
HIME
MATSUTAKE
A Japanese tablet formula uniting Iwade 101 fruiting-body powder with ITO-S mycelium and culture-filtrate extract.
150tablets5per dayMade in Japan
Why it is distinctive
One cultivated mushroom.
Two complementary fractions.
Hime Matsutake is the Japanese name used here for Agaricus blazei Murrill, a cultivated mushroom with a long history in Japanese functional-food research.
The formula does not rely on a single powder. It combines disrupted fruiting-body material from Iwade 101 with an ITO-S mycelium and culture-filtrate extract concentrate.
Ingredient study · cultured mycelium
A branching network.
A complex polysaccharide story.
Follow the ingredient story from cultured mushroom mycelium to its branching polysaccharide structures and the complete preparation.
Explore ingredient evidenceYOTSUBA JAPAN / FORMULA STUDY
01/ 03
Mycelial network
The mycelium is the branching growth network of the mushroom used in the ITO-S ingredient.
Illustrative ingredient study. Shapes and movement are simplified; product evidence is reviewed separately.
Formula architecture
One daily system.
Four source layers.
Inside the formula · per 5-tablet daily serving
Two mushroom fractions.
One verified label basis.
Five tablets weigh 1.25 g. The 1,250 mg mushroom declaration is an equivalent amount stated on the label, while 15 mg is the guaranteed mannan polysaccharide–protein component.Hime Matsutake dual mushroom complex
The Japanese label states that five tablets are equivalent to 1,250 mg of combined Himematsutake mycelium extract and disrupted fruiting-body material.
Mannan polysaccharide–protein complexes
A guaranteed component declared for the five-tablet daily serving; the pack also identifies β-(1→3) and β-(1→6)-D-glucan–protein complexes.
Ginkgo biloba leaf extract
A supporting botanical extract listed after the two Himematsutake ingredients in the current Japanese composition.
Vitamin C, vitamin B2 & folic acid
Three micronutrients complete the current tablet composition; individual quantities are not stated on the available Japanese panel.
A compact Japanese tablet ritual
Mushroom research heritage.
Designed for everyday use.
The brown triangular tablets bring the two mushroom-derived fractions, their guaranteed polysaccharide–protein component, ginkgo and selected vitamins into one 30-day format.
Five tablets daily150-tablet amber glass bottle30-day professional programme
Ingredient evidence library
Evidence, with the
right boundaries.
Important distinctionThe sources below examine specified Iwade 101 or ITO-S preparations, isolated complexes, mycelium extracts or other Agaricus products. They are not clinical trials of this complete Yotsuba formula.
Iwade strain 101Preclinical ingredient study
The ATOM polysaccharide–protein complex
A 1997 mouse study examined an ATOM complex prepared from Iwade strain 101. It is useful for understanding historical ingredient research, but it is not a human trial and does not establish an outcome for this finished product.
Iwade strain 101 extractPreclinical safety study
Genotoxicity and 13-week dietary safety
A published safety programme evaluated a specified Iwade strain 101 extract in standard genetic-toxicology tests and a 13-week rat study. The tested extract and doses are not equivalent to the complete Yotsuba tablet.
Agaricus blazei MurrillPhase I human study
Six-month tolerability research
A small phase I study assessed another Agaricus blazei supplement in people in cancer remission. It primarily informs tolerability at the tested doses and must not be read as efficacy evidence for Hime Matsutake.
Iwade strain 101Human safety study
Double-blind repeated-intake safety report
A 2006 placebo-controlled report evaluated continued intake of a freeze-dried Iwade strain 101 preparation in 46 adults. It is useful as strain-specific safety context, but the preparation and intake level are not equivalent to this tablet formula.
ITO-S strain preparationExploratory clinical report
Published ATOP · ITO-S clinical report
A 2006 Japanese report described an ATOP · ITO-S preparation in people with advanced cancer. The report was small, uncontrolled and conducted alongside medical care; it cannot establish efficacy and is not a trial of this finished product.
Himematsutake myceliumLaboratory study
Mycelium extract and immune-checkpoint signalling
A 2021 cell study examined a subcritical-water extract of Himematsutake mycelium and measured changes in immune-checkpoint molecules and dendritic-cell maturation markers. This is in-vitro mechanistic research, not evidence of a clinical outcome or a test of the Yotsuba tablets.
Professional product data
Complete details,
clearly organised.
The verified Japanese label is used as the primary source where the photographed English panel contains inconsistent units or serving information.Complete ingredients & allergens01
Current Japanese composition: Himematsutake fruiting-body cell-wall-disrupted powder (manufactured in Japan), Himematsutake mycelium and culture-filtrate extract concentrate, ginkgo biloba leaf extract powder / crystalline cellulose, vitamin C, vitamin B2, shellac and folic acid.
Allergen information: No statutory allergen is separately declared on the available Japanese panel. Verify the approved destination-market label before sale.
Format & daily serving02
Format 150 tabletsDaily serving 5 tabletsSupply 30 daysTablet weight 250 mgNet content 37.5 gAlso available 75-tablet pouch
Nutrition per daily serving03
Energy 4.75 kcalProtein 0.235 gFat 0.035 gCarbohydrate 0.875 gSalt equivalent 0.001 g
Nutrition values are stated per five tablets (1.25 g).
Use, storage & precautions04
Take five tablets daily with water according to the current export directions. Store away from high temperature, humidity and direct sunlight. Because the formula contains ginkgo biloba, consult a qualified healthcare professional before use if taking anticoagulant or antiplatelet medication, managing a medical condition, preparing for surgery, pregnant or breastfeeding. Discontinue use if an adverse reaction occurs. This is a food supplement, not a medicine.
日本MADE
IN JAPAN
IN JAPAN
Japanese mushroom provenance
Two cultivated fractions,
completed in Japan.
The formula brings together Iwade 101 fruiting-body material and the ITO-S mycelium fraction in a 150-tablet product manufactured in Japan for professional export channels.
Frequently asked
Clear answers,
without overclaiming.
01What is the daily serving?+
The current export directions indicate five tablets daily with water. The Japanese panel also gives a general range of five to ten tablets; the approved destination-market label remains authoritative.
02What does 1,250 mg equivalent mean?+
It is the label-declared equivalent of the combined Himematsutake mycelium extract and disrupted fruiting-body material in five tablets. It should not be added again to the 1.25 g physical serving weight.
03Which mushroom fractions are included?+
The formula combines cell-wall-disrupted fruiting-body powder from the Iwade 101 strain with ITO-S mycelium and culture-filtrate extract concentrate.
04Why do the pack and publications spell the mushroom name differently?+
The pack uses Agaricus blazei Murill. Scientific publications commonly spell the author name Murrill, while modern taxonomic literature often uses Agaricus subrufescens for this cultivated mushroom.
05Are the cited studies trials of this finished product?+
No. They concern specific Agaricus preparations or isolated complexes. The complete Yotsuba formula has not been represented as clinically tested in the sources shown here.
Food supplement · Not a medicine
Product information is educational and intended for professional portfolio review. It is not medical advice and is not intended to diagnose, treat, cure or prevent disease. Suitability, permitted claims and labelling must be assessed for each destination market.Hime Matsutake · 30-day daily system