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Metabolic Balance · YJ026 · 30-day daily system
BLOOD SUGAR
SIRTMAX®
A precisely quantified Japanese botanical formula built around SIRTMAX® black turmeric extract and four glucose-conscious plant layers.
90capsules3per dayMade in Japan
Why it was created
Five botanicals.
One measured daily ritual.
SIRTMAX® places a proprietary 100 mg black-turmeric extract at the centre of a formula designed for professionally guided, glucose-conscious wellness routines.
Bitter melon, Salacia, organic mulberry leaf and Banaba complete the botanical architecture, with every principal ingredient quantified per daily serving.
Ingredient research · SIRT1 context
A botanical signature.
A research pathway.
The black-turmeric ingredient provides a research link to SIRT1 within a broader five-botanical formula.
Explore ingredient evidenceYOTSUBA JAPAN / FORMULA STUDY
01/ 03
SIRTMAX® extract
SIRTMAX® is the formula’s proprietary Kaempferia parviflora extract.
Illustrative ingredient study. Shapes and movement are simplified; product evidence is reviewed separately.
Formula architecture
Five measured botanicals.
One coherent system.
Inside the formula · per 3-capsule daily serving
Every principal botanical.
Precisely quantified.
Amounts are taken from the current product specification. Destination-market labels and permitted claims remain authoritative.Bitter melon extract
The largest quantified botanical layer in the current three-capsule daily serving.
SIRTMAX® black turmeric extract
A proprietary Kaempferia parviflora extract developed by Tokiwa Phytochemical and studied for SIRT1-related activity.
Salacia extract powder
A measured Salacia botanical extract within the glucose-conscious formula architecture.
Organic mulberry leaf powder
A whole-leaf botanical layer sourced from organically grown mulberry.
Banaba extract powder
The fifth measured botanical layer in the verified daily formula.
Authentic product presentation
Metallic gold.
Japanese precision.
Amber glass, a mirror-silver cap and the warm metallic label create a compact presentation designed for a refined daily supplement ritual.Ingredient evidence library
Evidence, with the
right boundaries.
Important distinctionThe sources below concern SIRTMAX® as a separate ingredient or other botanical preparations. They are not clinical trials of the complete Yotsuba Japan five-botanical formula.
SIRTMAX® · black turmericOfficial ingredient record
Developer overview of SIRTMAX®
Tokiwa Phytochemical identifies SIRTMAX® as its black-turmeric extract and summarises the ingredient's SIRT1-related research. This is first-party manufacturer material, not independent proof of a clinical outcome.
SIRTMAX® · black turmericMechanistic study
A defined polymethoxyflavonoid and human SIRT1
A 2021 Communications Biology paper reported direct activation of human SIRT1 by a defined polymethoxyflavonoid from Kaempferia parviflora. This is mechanistic evidence, not a clinical outcome trial of the finished formula.
SIRTMAX® · black turmericRandomised human study
100 mg daily in a small crossover trial
A 27-participant, double-blind crossover study evaluated 100 mg of SIRTMAX® for seven weeks and reported changes in body weight and fasting glucose. Its size and design require cautious interpretation; it did not test this complete five-botanical product.
SIRTMAX® · black turmericRandomised human study
SIRT1 expression in an 8-week ingredient study
A small double-blind, placebo-controlled study of 28 healthy Japanese adults evaluated 100 mg of a SIRTMAX®-containing preparation daily and reported increased SIRT1 mRNA expression. It was an ingredient study, not a trial of this complete formula.
Bitter melonRandomised human study
Bitter-gourd supplementation in prediabetes
A 2025 controlled study investigated a different bitter-gourd fruit preparation in adults with prediabetes. It helps frame ingredient research but is not equivalent to this 225 mg extract or the complete product.
Salacia reticulataRandomised human study
Salacia extract in a metabolic study
A small double-blind study assessed specified Salacia leaf and root-bark extracts in adults with type 2 diabetes. The preparation and dose differ from the Salacia ingredient used here.
Mulberry leafRandomised human study
DNJ-enriched mulberry leaf and meal response
A controlled study examined a DNJ-enriched mulberry leaf extract and post-meal glycaemic markers. SIRTMAX contains organic mulberry leaf powder, not the same standardised extract.
BanabaRandomised human study
Banaba in metabolic-syndrome research
A controlled clinical study evaluated a specified Banaba preparation in adults with metabolic syndrome. It is relevant to the botanical evidence landscape but does not establish an outcome for this finished product.
Professional product data
Complete details,
clearly organised.
The quantitative formula is presented above. Here, professionals can review the complete ingredient declaration, nutrition panel, format, directions and handling information.Complete ingredients & allergens01
Current Japanese composition: Bitter melon extract (manufactured in India), black turmeric extract preparation (black turmeric extract, dextrin), Salacia extract powder, maltodextrin, organic mulberry leaf powder, Banaba extract preparation (dextrin, Banaba extract), microcrystalline cellulose, HPMC, magnesium carbonate, calcium stearate, silicon dioxide and caramel colour.
Allergen information: No mandatory allergen is identified in the available current ingredient declaration. The approved market-specific label remains authoritative.
Format & daily serving02
Format 90 capsulesDaily serving 3 capsulesSupply 30 daysServing weight 1.17 gAlso available 45-capsule pouch
Nutrition per daily serving03
Energy 4.48 kcalProtein 0.07 gFat 0.05 gCarbohydrate 0.93 gSalt equivalent 0.005 gBasis per 3 capsules
Use, storage & precautions04
Take three capsules daily with water or warm water according to the current directions. Store away from high temperature, humidity and direct sunlight. People taking medication, receiving medical treatment, pregnant or breastfeeding should consult a qualified healthcare professional before use. Keep out of reach of children. This is a food supplement, not a medicine.
日本MADE
IN JAPAN
IN JAPAN
Japanese quality & provenance
A proprietary extract,
completed in Japan.
SIRTMAX® is a registered trademark of Tokiwa Phytochemical Co., Ltd. The finished 90-capsule botanical formula is manufactured in Japan for professional export channels.
Frequently asked
Clear answers,
without overclaiming.
01What is SIRTMAX®?+
SIRTMAX® is a proprietary black-turmeric extract from Kaempferia parviflora developed by Tokiwa Phytochemical. The verified daily serving of this product supplies 100 mg.
02Does this product ‘raise sirtuins’?+
Ingredient research reports direct SIRT1 enzyme activation by a defined Kaempferia compound, while a separate small human ingredient study reported higher SIRT1 mRNA expression. This does not show a guaranteed rise in every sirtuin or establish an effect of the complete five-botanical formula.
03What is the daily serving?+
The current directions indicate three capsules daily with water or warm water, providing a 30-day supply.
04Can it be used with glucose-lowering medication?+
Anyone taking medication, including glucose-lowering medicines, or being treated for a medical condition should consult a qualified healthcare professional before use.
05Are the cited publications trials of this finished product?+
No. They concern SIRTMAX® as a separate ingredient or other botanical preparations. They do not establish a guaranteed outcome for the complete Yotsuba Japan formula.
Food supplement · Not a medicine
Product information is educational and intended for professional portfolio review. It is not medical advice and is not intended to diagnose, treat, cure or prevent disease. Suitability, permitted claims and labelling must be assessed for each destination market.Blood Sugar Support SIRTMAX® · Metabolic Balance